Tsiaj Me Me Hauv Vivo Imaging System

Tsiaj Me Me Hauv Vivo Imaging System GAni PA, GAni-Plus, GAni-OPO, GAni-OPO MAX lMulti-modal (Photoacoustic, Ultrasonic) hauv vivo imaging lMicron-level Resolution mus txog 3μm, millimeter-theem duab qhov tob txog 6mm 3D Merged Kev yees duab

Photoacoustic Non-invasive Hauv Vivo System

Tus Thawj Coj hauv Multi-modal Hauv Vivo Imaging Technology

Photoacoustic, ultrasound multimodal duab

Photoacoustic imaging raws li cov endogenous los yog exogenous lub teeb absorbing tshuaj xws li pigments, hlab ntsha, lipids, thiab nanoprobes

Ultrasound imaging raws li acoustic impedance sib txawv

Tsim ib qho ntxiv rau cov duab kho qhov muag thiab cov duab kho mob uas twb muaj lawm.

Photoacoustic microscopy lov los ntawm qhov kev txwv tsis pub tshaj ntawm cov duab kho qhov muag, thiab cov duab tob txog li 6 hli.

Nyob rau hauv cov duab tob tob, kev daws teeb meem siab ntawm qhov kho qhov muag tseem tuaj yeem khaws cia nrog qhov tseeb ntawm 3 μm.

3D duab cov ntaub ntawv yog soj ntsuam txheej los ntawm txheej

Los ntawm lub sijhawm tiag tiag 2D tomographic cov ntaub ntawv nthuav tawm, cov duab 3D ntawm cov ntaub so ntswg hauv zos tuaj yeem tau ntxiv, thiab cov duab 2D thiab 3D tuaj yeem txheeb xyuas ntxiv los ntawm kev siv cov ntaub ntawv ua software.

Non-invasive, daim ntawv lo-dawb duab

Tsuas yog ib qho me me ntawm cov dej (couplant) yog siv rau qhov chaw thaij duab kom phim lub teeb liab, thiab cov duab tsis pom ntawm qhov chaw sim tuaj yeem ua tiav yam tsis muaj kev txhaj tshuaj ntawm tus neeg sawv cev sib txawv.

Cua sov- tshuaj loog-kev koom ua ke me me tsiaj fixation rooj

Integrated cua sov-tshuaj loog ntaus ntawv tshwj xeeb tsim los tiv thaiv zoo dua ntawm cov qauv tsiaj.

Customized Ib wavelength, multi-wavelength, tunable wavelength ntau lub teeb

Ib txhij ua tiav 532 nm & 1064 nm & NIR-I / NIR-llimaging kom tau raws li ntau yam kev xav tau ntawm kev sim.

Photoacoustic imaging: pulsed laser irradiation, thermal expansion stress ultrasound, thiab ultrasound transducer nrhiav thiab reconstruction ntawm lub teeb haum tis nyob rau hauv cov ntaub so ntswg.

Lub paj hlwb ua haujlwm, lub paj hlwb lymphatic system, cerebral hlab ntsha.

Kev ua haujlwm ntawm cov qog thiab molecular probes.

Cov kab mob visceral (hepatic lobules, mesentery, retina, thiab lwm yam).

Multimodal Me Tsiaj Hauv Vivo Imaging System sawv cev rau kev daws teeb meem zoo tshaj plaws rau cov tsiaj me. Nws koom ua ke ntau hom kev yees duab los ua cov haujlwm ua haujlwm zoo. Nws tso cai rau kev tshawb nrhiav thiab kev tshuaj xyuas ntawm ntau yam ntsig txog tsiaj me, suav nrog lawv lub cev lub cev, cov kab mob pathological, thiab cov teebmeem ntawm cov tshuaj. Qhov kev koom ua ke ntawm kev yees duab yees tsis yog tsuas yog txhim kho qhov tseeb thiab kev ua haujlwm ntawm cov txheej txheem duab tab sis kuj muab cov ntaub ntawv ntau dua thiab muaj txiaj ntsig zoo uas yog qhov tseem ceeb rau kev nce qib ntawm kev tshawb fawb biomedical thiab kev txhim kho cov tshuaj.

Tsiaj Me Me Hauv Vivo Imaging System tau nrov zuj zus vim lawv qhov zoo heev. Nov yog qee qhov txiaj ntsig tseem ceeb ntawm cov khoom no:

1. Optical/photoacoustic/ultrasound peb-modal imaging
Peb-modal nyob rau hauv vivo me tsiaj imaging system uas integrates optical microscopy, photoacoustic imaging ntawm endogenous lub teeb-absorbing tshuaj xws li pigments thiab hlab ntsha, thiab ultrasound imaging ntawm acoustic impedance txawv.

2. Micron-theem daws teeb meem, millimeter-theem duab qhov tob
Micron, cov duab daws teeb meem siab ntawm cov ntaub so ntswg hauv 3 hli tseem tuaj yeem ua tau yam tsis tas yuav tsum muaj qhov sib piv ntawm cov xov xwm, thiab txoj haujlwm ntawm kev tsom xam tuaj yeem hloov kho raws li lub sijhawm tiag tiag ntawm cov software.

3. Cov ntaub ntawv duab peb sab yog txheeb xyuas cov txheej txheem
Los ntawm lub sijhawm tiag tiag 2D tomographic cov ntaub ntawv nthuav tawm, cov duab 3D ntawm cov ntaub so ntswg hauv zos tuaj yeem tau ntxiv, thiab cov duab 2D thiab 3D tuaj yeem txheeb xyuas ntxiv los ntawm kev siv cov ntaub ntawv ua software.

4. Tsis muaj kev cuam tshuam, tsis muaj daim ntawv lo
Tsuas yog ib qho me me ntawm cov dej (couplant) yog siv rau qhov chaw thaij duab kom phim lub teeb liab, thiab cov duab tsis pom ntawm qhov chaw sim tuaj yeem ua tiav yam tsis muaj kev txhaj tshuaj ntawm tus neeg sawv cev sib txawv.

5. Cua sov-tso tshuaj loog-kev koom ua ke me me tsiaj fixation rooj
Integrated cua sov-tshuaj loog ntaus ntawv tshwj xeeb tsim los tiv thaiv zoo dua ntawm cov qauv tsiaj.

6. Cov duab kos duab nrog cov teeb pom kev zoo
Raws li cov kev xav tau sib txawv ntawm cov neeg siv khoom, kho qhov sib txuas ib leeg-yav, ntau lub wavelength, tunable wavelength teeb pom kev zoo.

Tsiaj Me Me Hauv Vivo Imaging System tau siv dav hauv cheeb tsam hauv qab no

1. Kev saib xyuas cov txheej txheem qog nqaij hlav
Kev saib xyuas kev loj hlob ntawm cov qog trophic cov hlab ntsha hauv pob ntseg ntawm nas, kev saib xyuas kev loj hlob ntawm cov qog trophic cov hlab ntsha, thiab kev sib raug zoo ntawm qhov curvature, ntom thiab qhov tob ntawm cov qog trophic cov hlab ntsha thiab lub sij hawm loj hlob ntawm cov qog nqaij hlav.

Cov ntaub ntawv
[1]. F. Yang, et al..J. Biophotonics, e202000022.2020.DOI: 10.1002/-jbio.20000022
[2]. Z. Wang, Nanophotonics, 10(12), 3359-3368, 2021.DOI:10.1515/nanoph-2021-0198.

2. Kev saib xyuas cov txheej txheem kho cov qog
Kev saib xyuas ntawm ablation ntawm cov hlab ntsha nourishing thaum lub sij hawm photodynamic (PDT) kho cov qog rov qab hauv cov nas tau pom, thiab kev sib raug zoo ntawm qhov curvature, ntom thiab qhov tob ntawm cov hlab ntsha trophic thiab lub sijhawm ntawm PDT kev kho mob tau tshwm sim.

Cov ntaub ntawv
F. Yang, et al., J. Biophotonics, e202000022.2020, DOI:10.1002/-jbio.20000022.

3. Kev ua haujlwm ntawm lub hlwb hauv cov tsiaj me
Kev soj ntsuam dynamic ntawm "ischemia-reperfusion" ntawm vascular network sib sib zog nqus hauv nas hlwb tau pom, thiab cov ntawv thov dav dav ntawm cov cuab yeej no hauv kev tshawb fawb ntawm cov kab mob cerebrovascular tau tshwm sim.

Cov ntaub ntawv
F.Yang. et al.. J. Biophotonics, e202000022.2020.DOI:10.1002/- jbio.20000022

4. Ntsuas seb cov ntshav txaus rau qhov mob li cas
Kev soj ntsuam ntawm qib ntshav muab rau cov nas tom qab thiab tag nrho cov nas khiav tawm tau pom, uas tau tawg los ntawm lub fwj ntawm cov cuab yeej siv tshuaj ntsuam xyuas cov qib ntshav rau cov ntaub so ntswg puas thiab txhim kho qhov muaj peev xwm ntawm kev phais mob sai.

Cov ntaub ntawv
D.Zhang.et al., Quant Imaging Med Surg, 11(10).4365-4374.2021.DOI:10.21037/qims-21-135.

5. Kev yees duab ntawm iris thiab sclera hauv cov tsiaj muaj sia
Nws tuaj yeem paub txog cov duab ntawm iris thiab cov hlab ntsha ntawm lub qhov muag ntawm cov tsiaj me (xws li nas) thiab tsiaj loj (xws li luav).

6. Nanoprobes thiab molecular imaging kev tshawb fawb
Tumor-specific photoacoustic imaging ntawm tshwj xeeb wavelengths (kev cai version)
Lub photoacoustic multi-modal me me tsiaj imager tuaj yeem hloov kho, thiab cov nanoprobe tshwj xeeb tuaj yeem siv los txhim kho qhov amplitude ntawm photoacoustic imaging teeb liab ntawm cov qog nqaij hlav rau qhov tshwj xeeb wavelengths, thiaj li ua tiav qhov loj-qhov tob thiab siab-sensitivity qog-specific. photoacoustic duab.

Cov ntaub ntawv
[1]. D.Cui, et al.. Nano Letters, 21(16).6914-6922.2021, DOI:10.1021/acs. nanolett.1c02078[2]. J.Zheng. et al., J. Am. Chem. Soe, 141(49),{12}}.2019.DOI: 10.1021/jacs.9b10353.

7. Cov qog nqaij hlav mis kuaj cov cim kos duab
T.Wong.et_x0001_al.. _x0001_Sci.Adv.,3_x0001_(5). _x0001_e1602168.2017.D01:_x{13}}.1126/sciadv.1602168.
Daim ntawv teev cov duab ntawm daim siab micrometastases nyob rau hauv thaum ntxov-theem neoma
Q.Yu,et_x0001_al.,J_x0001_Nucl_x0001_Med. 61(7),10791085,2020.

8. Ambulatory saib xyuas ntawm cov qauv thiab kev ua haujlwm hloov pauv hauv cov theem pib ntawm abscient stroke
J.Lv.et_x0001_al.,_x0001_Theranostics,10(2).816-828.2020.DOI:10.7150/thno 38 554.
Multimodal imaging kev soj ntsuam ntawm lub qhov muag nyob ua ntej thiab tom qab suture raug mob
J.Park.B.Park.et_x0001_al.,_x0001_PNAS.118(11)._x{{7 }}e1920879118.2021,_x0001_DO1:10.1073/pnas.1920879118.
Daim duab ntawm retina hauv cov tsiaj muaj sia, choroid, iris, sclera
C.Tian,{{0}}x0001_et_x0001_al.,_x0001_0ptics{{6} }x0001_Express,25(14).
Z.Hosseinace,{{0}}x0001_et_x0001_al.,_x0001_Optics{{6} }x0001_Leters,45(22).{10}},2020.DOI:10.1364/0L.410171.
Labeled duab ntawm cov cell hauv lub siab
D. Deng.et_x0001_al.,Nanophotonics,2021,DOI:/10.1515/nanoph-2021-0281.

9. Kev ntsuas ntau ntawm cov xim xaum
Lub photoacoustic multimodal imaging system tuaj yeem ntsuas qhov ntau ntawm cov tawv nqaij pigmentation thiab pab kuaj mob.

Cov ntaub ntawv
H. Ma. et al., Appl, Phys, Lett.. 113,083704,2018.DOI:10.1063/1.5041769.

10. Kev ntsuam xyuas microvascular quantitative
Lub photoacoustic multimodal imaging system muaj peev xwm saib xyuas cov nyhuv ntawm ci erythema ua ntej thiab tom qab kev kho mob, thiab muab cov lus pom zoo tshaj plaws ntawm cov kab mob pathological.

Kev siv

H. Ma. thiab al.. Bio. Exp.12(10).6300-6316.2021.DOI:10.1364/B0E.439625.
Ob-dimensional assessment Peb-dimensional quantification Pre- and post-treatment evaluation

Cim npe nrov: Me tsiaj nyob rau hauv vivo imaging system, Tuam Tshoj me tsiaj nyob rau hauv vivo imaging system manufacturers, lwm tus neeg, hoobkas